5 Amino-1MQ

Description

DESCRIPTION

5-Amino-1MQ is a small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor widely explored for its role in metabolic regulation, adipocyte signaling, and NAD⁺-related biochemical pathways. Research models have investigated how NNMT inhibition may influence cellular energy balance, lipolytic activity, and mitochondrial efficiency. Its relevance in metabolic-science research has made it a common investigative tool in controlled laboratory settings.

LYOPHILIZED PEPTIDES

This compound is provided in lyophilized form to preserve purity, structural integrity, and long-term stability. No fillers or excipients are used in the lyophilization process.

RESEARCH APPLICATIONS

1 — Metabolic Regulation & NNMT Pathways

5-Amino-1MQ is used in research to study how NNMT inhibition influences NAD⁺ metabolism, energy output, and biochemical stress responses in adipocytes. Studies indicate that NNMT plays a role in regulating SAM (S-adenosyl methionine) utilization and downstream methylation pathways. (References: https://pubmed.ncbi.nlm.nih.gov/31337796/)

2 — Mitochondrial Efficiency & Cellular Energy Balance

Preclinical work suggests NNMT inhibition may improve mitochondrial oxidation efficiency and help regulate ATP production under metabolic-stress conditions. 5-Amino-1MQ is commonly used to examine mitochondrial bioenergetics and adaptive thermogenic responses. (References: https://pubmed.ncbi.nlm.nih.gov/26746420/)

3 — Adipocyte Behavior & Lipid Mobilization

Investigators use 5-Amino-1MQ to examine its effects on adipocyte morphology, lipid oxidation pathways, and shifts in metabolic phenotype associated with NNMT suppression. These models help define how NNMT influences lipid turnover and inflammatory signaling. (References: https://pubmed.ncbi.nlm.nih.gov/31578236/)

 

SPECIFICATIONS

Property | Details

— | —

Compound Name | 5-Amino-1MQ

Chemical Class | NNMT inhibitor

CAS Number | 1034048-43-3

Appearance | White to off-white lyophilized powder

Purity | ≥ 99% (HPLC verified)

Solubility | Soluble in standard laboratory solvents

Storage | Store dry at 2–8 °C; after reconstitution refrigerate ≤ 30 days

Usage | For laboratory research only · Use standard protective protocols

 

Research Data & References

– NNMT inhibition metabolism research: https://pubmed.ncbi.nlm.nih.gov/31337796/

– Mitochondrial bioenergetic regulation: https://pubmed.ncbi.nlm.nih.gov/26746420/

– Adipocyte metabolic signaling studies: https://pubmed.ncbi.nlm.nih.gov/31578236/

 

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.