Description

DESCRIPTION

SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) extensively researched for its role in mitochondrial stabilization, cardiolipin interaction, electron-transport-chain optimization, and protection against oxidative stress. Studies explore its effects on ATP generation, mitochondrial membrane integrity, cellular resilience, and bioenergetic performance across cardiac, neural, muscular, and metabolic research models.

LYOPHILIZED PEPTIDES

This peptide is supplied in sterile, freeze-dried (lyophilized) form to preserve purity, molecular stability, and long-term integrity. No fillers or excipients are added.

RESEARCH APPLICATIONS

1 — Mitochondrial Stabilization & Bioenergetic Function

SS-31 is widely studied for binding to cardiolipin in the inner mitochondrial membrane, helping stabilize electron transport, reduce ROS production, and improve ATP output. Research examines its role in supporting mitochondrial efficiency under metabolic or oxidative stress.

(References: PubMed—https://pubmed.ncbi.nlm.nih.gov/25738459/, Nature—https://www.nature.com/articles/s41467-022-35804-2 )

2 — Oxidative-Stress Reduction & Cellular Protection

Laboratory models show SS-31 may mitigate oxidative damage, support antioxidant enzyme function, and regulate mitochondrial stress-response pathways. It is commonly used in research on cellular resilience and injury-response modeling.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S2212877822001063, PubMed—https://pubmed.ncbi.nlm.nih.gov/23113316/ )

3 — Cardiac, Neural & Muscular Research Models

SS-31 has been evaluated in models of cardiac tissue stress, skeletal muscle fatigue, neurodegeneration, and metabolic decline. Its mitochondrial-targeting activity allows for detailed study of tissue-specific energetic and protective pathways.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fnins.2019.01129/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/36677050/ )

SPECIFICATIONS

Property | Details

Peptide Name | SS-31 (Elamipretide)

Amino Acid Sequence | D-Arg-Dmt-Lys-Phe-NH₂

Molecular Formula | C34H56N10O5

Molecular Weight | ~748.9 g/mol

CAS Number | 127463-70-5

Purity | ≥ 99% (HPLC verified)

Appearance | White to off-white lyophilized powder

Solubility | Soluble in bacteriostatic/sterile water

Storage | Store dry at 2–8 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– Mitochondrial biogenesis & ATP support: https://pubmed.ncbi.nlm.nih.gov/25738459/

– Oxidative-stress and protective signaling: https://pubmed.ncbi.nlm.nih.gov/23113316/

– Tissue-specific mitochondrial studies: https://pubmed.ncbi.nlm.nih.gov/36677050/

Research Disclaimer

RESEARCH USE ONLY.
This product is not intended for therapeutic or diagnostic use. EOC Labs products are sold strictly for laboratory research and analytical purposes only. All information provided by EOC Labs, including descriptions, references, and technical data, is intended solely for educational and informational purposes. Statements have not been evaluated by the U.S. Food and Drug Administration (FDA). No claims are made for any medical or consumer application. By purchasing this product, the buyer certifies that it will be handled by qualified professionals in a properly equipped laboratory and used in compliance with all applicable local, state, and federal laws and regulations.