Description

DESCRIPTION

Sermorelin is a synthetic 29–amino‑acid fragment of Growth Hormone–Releasing Hormone (GHRH 1‑29), extensively used in laboratory research to study pituitary GH stimulation, hypothalamic regulatory signaling, endocrine feedback loops, and age‑related changes in GH secretion. Studies explore its influence on GH/IGF‑1 pathways, pulsatile secretion dynamics, and metabolic/endocrine response models under controlled experimental conditions.

LYOPHILIZED PEPTIDES

This peptide is supplied as a sterile, freeze‑dried (lyophilized) powder to maintain purity, structural stability, and long‑term integrity. No fillers or excipients are added.

RESEARCH APPLICATIONS

1 — Pituitary GH Release & Endocrine Regulation

Sermorelin is widely used to investigate GHRH‑receptor activation, pulsatile GH release, IGF‑1 modulation, and endocrine‑axis modeling. Research evaluates its short‑acting properties and physiologic GH‑cycle behavior.

(References: Nature—https://www.nature.com/articles/ijo2013172, PubMed—https://pubmed.ncbi.nlm.nih.gov/2699646/ )

2 — Hypothalamic Signaling & Aging‑Related GH Decline

Studies examine how Sermorelin influences hypothalamic regulation, age‑related changes in GH rhythm, and neuroendocrine communication within the GH/IGF‑1 system.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0026049522001033, PubMed—https://pubmed.ncbi.nlm.nih.gov/24516338/ )

3 — Cellular Repair, Protein Synthesis & Metabolic Studies

Research models explore Sermorelin for its role in protein‑synthesis pathways, metabolic recovery, cellular‑repair signaling, and growth‑factor–related mechanisms.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fendo.2021.791797/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/17163493/ )

SPECIFICATIONS

Property | Details

Peptide Name | Sermorelin

Amino Acid Sequence | Tyr‑Ala‑Asp‑Ala‑Ile‑Phe‑Thr‑Asn‑Ser‑Tyr‑Arg‑Lys‑Val‑Leu‑Gly‑Gln‑Leu‑Ser‑Ala‑Arg‑Lys‑Leu‑Leu‑Gln‑Asp‑Ile‑Met‑Ser

Molecular Formula | C149H246N44O42S

Molecular Weight | ≈ 3358.0 g/mol

CAS Number | 86168‑78‑7

Purity | ≥ 99% (HPLC verified)

Appearance | White to off‑white lyophilized powder

Solubility | Soluble in sterile/bacteriostatic water

Storage | Store dry at 2–8 °C; refrigerate after reconstitution

Usage | Laboratory research only

Research Data & References

– GH secretion & pituitary activity: https://pubmed.ncbi.nlm.nih.gov/2699646/

– Endocrine modeling & GHRH studies: https://pubmed.ncbi.nlm.nih.gov/17163493/

Research Disclaimer

RESEARCH USE ONLY.
This product is not intended for therapeutic or diagnostic use. EOC Labs products are sold strictly for laboratory research and analytical purposes only. All information provided by EOC Labs, including descriptions, references, and technical data, is intended solely for educational and informational purposes. Statements have not been evaluated by the U.S. Food and Drug Administration (FDA). No claims are made for any medical or consumer application. By purchasing this product, the buyer certifies that it will be handled by qualified professionals in a properly equipped laboratory and used in compliance with all applicable local, state, and federal laws and regulations.