Tirzepatide

Description

DESCRIPTION

Tirzepatide is an acylated synthetic polypeptide studied as a dual GIP and GLP‑1 receptor agonist. Research explores its effects on insulin secretion, glucagon suppression, glucose regulation, body‑weight modulation, gastric emptying, and appetite‑signaling pathways. Its long‑acting structure allows detailed study of incretin biology, metabolic regulation, and whole‑system energy‑balance models.

LYOPHILIZED PEPTIDES

This peptide is provided in a sterile, lyophilized (freeze‑dried) form to preserve purity, structural integrity, and long‑term molecular stability. No fillers or excipients are used in the formulation.

RESEARCH APPLICATIONS

1 — Glucose Regulation & Glycemic Modeling

Studies evaluate tirzepatide’s influence on insulin secretion, β‑cell responsiveness, hepatic glucose output, and dual‑agonist signaling in controlled metabolic research.

(References: Nature—https://www.nature.com/articles/s41591-023-02590-2, PubMed—https://pubmed.ncbi.nlm.nih.gov/37365087/ )

2 — Obesity & Weight‑Management Pathways

Research explores tirzepatide’s effects on appetite signaling, hypothalamic regulation, caloric‑intake modeling, thermogenesis, and metabolic‑rate behavior.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S1550413123002073, PubMed—https://pubmed.ncbi.nlm.nih.gov/37581871/ )

3 — Hepatic, Lipid & Metabolic‑Liver Studies

Tirzepatide is used in research involving hepatic fat turnover, triglyceride pathways, lipid‑clearance behavior, and liver‑centric metabolic modeling.

(References: MDPI—https://www.mdpi.com/1422-0067/24/3/2341, PubMed—https://pubmed.ncbi.nlm.nih.gov/36638174/ )

4 — Cardiometabolic, Renal & Systemic Metabolism

Research evaluates tirzepatide in multi‑organ metabolic models including kidney filtration markers, lipid modulation, cardiovascular energy balance, and systemic inflammatory markers.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fendo.2023.1211441/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/36971244/ )

SPECIFICATIONS

Property | Details

Peptide Name | Tirzepatide

Synonyms | LY3298176, “Twincretin”

Amino Acid Classification | Acylated synthetic polypeptide (dual agonist)

CAS Number | 2023788‑19‑2

Molecular Weight | ~4813 Da

Purity | ≥ 99% (HPLC verified)

Appearance | White to off‑white lyophilized powder

Solubility | Soluble in sterile/bacteriostatic water

Storage | Store dry at −20 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– Dual GIP/GLP‑1 metabolic research: https://pubmed.ncbi.nlm.nih.gov/37365087/

– Glycemic‑control comparative studies: https://pubmed.ncbi.nlm.nih.gov/37581871/

– Hepatic‑fat & metabolic‑liver data: https://pubmed.ncbi.nlm.nih.gov/36638174/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.