Ipamorelin

Description

DESCRIPTION

Ipamorelin is a highly selective ghrelin-receptor (GHSR) agonist widely studied for its ability to stimulate growth hormone (GH) release without significantly impacting cortisol, prolactin, or ACTH. As a pentapeptide with clean receptor specificity, Ipamorelin is used to investigate endocrine signaling, metabolic regulation, mitochondrial function, protein synthesis, and tissue-repair cascades in controlled laboratory environments.

LYOPHILIZED PEPTIDES

This peptide is provided in lyophilized powder form to preserve purity, structural integrity, and long-term stability. No fillers or excipients are used during lyophilization.

RESEARCH APPLICATIONS

1 — Selective GH Release & Endocrine Modeling

Ipamorelin selectively activates the ghrelin receptor (GHSR), producing clean GH pulses without altering stress hormones. Research models examine its role in pituitary activation, pulsatile GH release, IGF‑1 modulation, and endocrine rhythm modeling.

(References: PubMed—https://pubmed.ncbi.nlm.nih.gov/17374712/, Nature—https://www.nature.com/articles/ijo2013172 )

2 — Tissue Repair, Protein Synthesis & Cellular Recovery

Studies show Ipamorelin may support anabolic signaling, fibroblast activation, collagen-related pathways, and tissue-repair processes mediated through GH-induced mechanisms. It is frequently applied in models of structural recovery and regeneration.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0026049522001033, PubMed—https://pubmed.ncbi.nlm.nih.gov/18031563/ )

3 — Metabolic Support & Mitochondrial Activity

Ipamorelin has been researched for its potential effects on mitochondrial biogenesis, lipid oxidation, glucose utilization, and cellular energy turnover. Its selective GH profile allows researchers to study metabolic efficiency, bioenergetics, and anti-aging mechanisms.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fendo.2021.791797/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/28737940/ )

SPECIFICATIONS

Property | Details

Peptide Name | Ipamorelin

Amino Acid Sequence | H-Aib-HomoPhe-Ala-Trp-D-Phe-Lys-NH₂

Molecular Formula | C38H49N9O5

Molecular Weight | ≈ 711.9 g/mol

CAS Number | 170851-70-4

Purity | ≥ 99% (HPLC verified)

Appearance | White to off-white lyophilized powder

Solubility | Soluble in bacteriostatic/sterile water

Storage | Store dry at 2–8 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– GH secretion & receptor modeling: https://pubmed.ncbi.nlm.nih.gov/17374712/

– Protein synthesis & recovery pathways: https://pubmed.ncbi.nlm.nih.gov/18031563/

– Mitochondrial activity & metabolic regulation: https://pubmed.ncbi.nlm.nih.gov/28737940/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.