Epithalon

Description

DESCRIPTION

Epithalon (Epitalon / Epithalamin) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its role in telomerase modulation, cellular aging pathways, pineal-gland biochemistry, DNA protection, and circadian-regulation mechanisms. Research explores its influence on chromosomal stability, melatonin cycles, oxidative-stress pathways, and longevity-associated cellular signaling models.

LYOPHILIZED PEPTIDES

This peptide is provided as a sterile, freeze-dried (lyophilized) powder to maintain molecular stability, purity, and long-term integrity. No fillers or excipients are added.

RESEARCH APPLICATIONS

1 — Telomerase Activity & Chromosomal Stability

Epithalon has been extensively studied for telomerase activation, telomere-length dynamics, chromosomal protection, and genomic stability in cellular aging models.

(References: PubMed—https://pubmed.ncbi.nlm.nih.gov/15247010/, MDPI—https://www.mdpi.com/1422-0067/18/5/984 )

2 — Pineal Gland, Melatonin & Circadian Biology

Research evaluates Epithalon’s influence on pineal-gland peptide pathways, melatonin secretion cycles, sleep–wake regulation, and circadian-modeling systems.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0306453018304974, PubMed—https://pubmed.ncbi.nlm.nih.gov/16595040/ )

3 — Oxidative Stress, Mitochondrial Protection & Anti-Aging Mechanisms

Laboratory models explore Epithalon’s involvement in oxidative-stress reduction, mitochondrial integrity, protein-carbonyl regulation, and long-term protective pathways.

(References: Nature—https://www.nature.com/articles/s41598-017-12189-1, Frontiers—https://www.frontiersin.org/articles/10.3389/fnagi.2020.00130/full )

4 — Cellular Longevity & Senescence Pathway Research

Epithalon is frequently evaluated in senescence models for its potential influence on DNA repair, cell-cycle regulation, apoptotic pathways, and longevity-associated biochemical networks.

(References: PubMed—https://pubmed.ncbi.nlm.nih.gov/22292466/, ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0047637423000245 )

SPECIFICATIONS

Property | Details

Peptide Name | Epithalon (Epitalon / Epithalamin)

Amino Acid Sequence | Ala-Glu-Asp-Gly

Molecular Formula | C14H22N4O9

Molecular Weight | ~390.35 g/mol

CAS Number | 307297-39-8

Purity | ≥ 99% (HPLC verified)

Appearance | White to off-white lyophilized powder

Solubility | Soluble in sterile/bacteriostatic water

Storage | Store dry at −20 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– Telomerase & genomic stability: https://pubmed.ncbi.nlm.nih.gov/15247010/

– Melatonin & circadian biology: https://pubmed.ncbi.nlm.nih.gov/16595040/

– Oxidative-stress & anti-aging studies: https://pubmed.ncbi.nlm.nih.gov/22292466/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.