CJC-1295 (No DAC)

Description

DESCRIPTION

CJC-1295 (No DAC), also known as Mod GRF (1-29), is a tetrasubstituted Growth Hormone–Releasing Hormone (GHRH) analog studied for its role in promoting pulsatile GH release and supporting endocrine regulatory pathways. Without the DAC component, this version maintains a shorter half-life, allowing researchers to evaluate natural GH cycling, pituitary receptor activation, and metabolic signaling dynamics across controlled laboratory models. Investigations often explore its effects on IGF-1 modulation, mitochondrial activity, and cellular repair responses.

LYOPHILYZED PEPTIDES

This peptide is supplied in lyophilized powder form to preserve molecular stability, purity, and structural integrity during storage. No fillers or excipients are used.

RESEARCH APPLICATIONS

1 — Growth Hormone Pulsatility & Endocrine Regulation

CJC-1295 (No DAC) has been widely researched for stimulating GHRH receptors in a natural pulsatile manner, enabling controlled GH-release modeling without prolonged elevation. Studies focus on its influence on pituitary activation, GH/IGF-1 signaling rhythms, and physiological endocrine behavior.

(References: Nature—https://www.nature.com/articles/ijo2013172, PubMed—https://pubmed.ncbi.nlm.nih.gov/18023546/ )

2 — Metabolic Function & Mitochondrial Support

Research suggests that Mod GRF (1-29) may contribute to IGF-1 regulation, mitochondrial biogenesis, and metabolic recovery in laboratory models. Investigators examine its potential cellular-repair effects and influences on energy-production pathways under metabolic stress.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0026049522001033, PubMed—https://pubmed.ncbi.nlm.nih.gov/28737940/ )

3 — Tissue Repair & Cellular Recovery

Models exploring GH-driven pathways often utilize CJC-1295 (No DAC) to evaluate wound-repair dynamics, structural restoration, and fibroblast activation patterns. Its short-acting nature allows researchers to examine dose-dependent and time-sensitive responses to peptide stimulation.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fendo.2021.791797/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/17163493/ )

SPECIFICATIONS

Property | Details

Peptide Name | CJC-1295 (No DAC) / Mod GRF (1-29)

Amino Acid Sequence | Tyr–Aib–Asp–Ala–Ile–Phe–Thr–Lys–Gln–Leu–Ser–Ala–Arg–Kys–Leu–Leu–Gln–Asp–Ile–Leu–Ser–Arg–Gln–Gln–Ala–His–Ala–Ile–NH₂

CAS Number | 863288-34-0

Molecular Weight | 3367.93 g/mol

Purity | ≥ 99% (HPLC verified)

Appearance | White to off-white lyophilized powder

Solubility | Soluble in bacteriostatic water

Storage | Store dry at 2–8 °C; after reconstitution refrigerate ≤ 30 days

Usage | Laboratory research only

Research Data & References

– GH pulsatility research: https://pubmed.ncbi.nlm.nih.gov/18023546/

– Endocrine signaling & receptor modeling: https://pubmed.ncbi.nlm.nih.gov/17163493/

– Metabolic pathways & mitochondrial activity: https://pubmed.ncbi.nlm.nih.gov/28737940/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.