CJC-1295 (No DAC) / Ipamorelin Blend

Description

DESCRIPTION

This research blend combines CJC-1295 (No DAC), a tetrasubstituted GHRH analog designed to promote natural pulsatile growth-hormone release, with Ipamorelin, a selective ghrelin-receptor (GHSR) agonist known for its targeted GH stimulation and minimal off-target effects. Together, these peptides are studied for their combined influences on endocrine signaling, metabolic balance, cellular repair, mitochondrial optimization, and recovery pathways across controlled laboratory systems.

LYOPHILYZED PEPTIDES

This blend is provided in lyophilized powder form to maintain structural stability, purity, and long-term molecular integrity. No fillers or excipients are used during the freeze‑drying process.

RESEARCH APPLICATIONS

1 — Growth Hormone Pulsatility & Endocrine Modulation

CJC‑1295 (No DAC) is widely studied for its ability to mimic natural GHRH-driven GH pulses without sustained elevation, while Ipamorelin stimulates GH release via GHSR without significantly altering cortisol or prolactin levels. Researchers evaluate this combination to analyze synchronized pituitary activation, GH cycling behavior, and IGF‑1 modulation.

(References: Nature—https://www.nature.com/articles/ijo2013172, PubMed—https://pubmed.ncbi.nlm.nih.gov/17374712/)

2 — Cellular Repair, Regeneration & Protein Synthesis

Both peptides have been evaluated for their ability to influence cellular recovery pathways, increase protein synthesis, and support tissue remodeling processes. Ipamorelin’s selective GH activation and CJC‑1295 No DAC’s pulsatile GH modulation create a dynamic environment for studying fibroblast activity, mitochondrial repair cycles, and anabolic signaling.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0026049522001033, PubMed—https://pubmed.ncbi.nlm.nih.gov/18031563/)

3 — Metabolic Regulation & Anti‑Aging Mechanisms

Laboratory models have explored how GH/IGF‑1–modulating peptides influence energy balance, lipid metabolism, mitochondrial biogenesis, and cellular stress responses. The CJC‑1295 No DAC + Ipamorelin combination is frequently used in research related to metabolic efficiency, bioenergetic optimization, and anti-aging biochemical pathways.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fendo.2021.791797/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/28737940/)

SPECIFICATIONS

Property | Details

Blend | CJC‑1295 (No DAC) 10mg + Ipamorelin 10mg (20mg total)

Amino Acid Sequences | CJC‑1295 No DAC (Mod GRF 1‑29): Tyr–Aib–Asp–Ala–Ile–Phe–Thr–Lys–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Leu–Ser–Arg–Gln–Gln–Ala–His–Ala–Ile–NH₂; Ipamorelin: H‑Aib‑HomoPhe‑Ala‑Trp‑D‑Phe‑Lys‑NH₂

Appearance | White to off‑white lyophilized powder

Purity | ≥ 99% (HPLC verified)

Molecular Weight | CJC-1295 No DAC ≈ 3367.93 g/mol; Ipamorelin ≈ 711.9 g/mol

Solubility | Soluble in bacteriostatic water

Storage | Store dry at 2–8 °C; after reconstitution refrigerate ≤ 30 days

Usage | Laboratory research only

Research Data & References

– GH pulsatility modeling: https://pubmed.ncbi.nlm.nih.gov/17374712/

– Cellular recovery & protein synthesis pathways: https://pubmed.ncbi.nlm.nih.gov/18031563/

– Endocrine signaling & metabolic regulation: https://pubmed.ncbi.nlm.nih.gov/28737940/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.