SNAP-8

Description

DESCRIPTION

SNAP-8 (Acetyl Octapeptide-3 / Acetyl Glutamyl Heptapeptide-3) is an extended analogue of Argireline, engineered to modulate the SNARE protein complex involved in neurotransmitter release at neuromuscular junctions. Research explores its potential relevance in cosmetic biochemistry, neuromodulation modeling, expression-line depth studies, and peptide–protein interaction pathways.

LYOPHILIZED PEPTIDES

This peptide is supplied as a freeze‑dried (lyophilized) powder to preserve purity, molecular structure, and long‑term stability. No fillers or excipients are added to the formulation.

RESEARCH APPLICATIONS

1 — Neuromodulation & SNARE-Complex Pathway Research

SNAP‑8 is studied for its biochemical interaction with the SNARE complex (SNAP-25, syntaxin, and VAMP), which regulates vesicle fusion and neurotransmitter release. Research explores whether peptide extensions enhance inhibitory interactions within neuromuscular models.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0022283616303225, PubMed—https://pubmed.ncbi.nlm.nih.gov/11257466/ )

2 — Expression-Line & Dermatologic Modeling

Research evaluates SNAP‑8 for its potential influence on expression-line formation via modulation of neurotransmitter release, making it relevant for cosmetic science and dermal‑model studies. Investigators assess wrinkle‑depth modeling and peptide‑based neuromodulation pathways.

(References: MDPI—https://www.mdpi.com/1422-0067/19/4/1078, Nature—https://www.nature.com/articles/s41598-017-12189-1 )

3 — Synergy With Other Cosmetic/Neuromodulatory Peptides

SNAP‑8 is frequently used in research to compare and analyze synergistic behavior with other peptides, including Argireline, GHK‑Cu, and acetylated peptide variants. Investigators study its potential to enhance formulation performance in laboratory systems.

(References: Frontiers—https://www.frontiersin.org/articles/10.3389/fphar.2021.808770/full, PubMed—https://pubmed.ncbi.nlm.nih.gov/25950459/ )

SPECIFICATIONS

Property | Details

Peptide Name | SNAP-8 (Acetyl Octapeptide-3)

Amino Acid Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂

Chemical Name | Acetyl Glutamyl Heptapeptide-3 / Acetyl Octapeptide-3

Molecular Formula | C41H70N16O16S

Molecular Weight | ~1073–1075 g/mol

CAS Number | 868844-74-0

Purity | ≥ 99% (HPLC verified)

Appearance | White lyophilized powder

Solubility | Soluble in bacteriostatic/sterile water

Storage | Store dry at 2–8 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– SNARE complex neuromodulation studies: https://pubmed.ncbi.nlm.nih.gov/11257466/

– Expression-line dermal pathways: https://www.mdpi.com/1422-0067/19/4/1078

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.