Selank

Description

DESCRIPTION

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunomodulatory peptide tuftsin. It has been widely studied for its potential influence on GABAergic signaling, monoamine neurotransmission, BDNF expression, and stress-regulation pathways in controlled laboratory models. Research applications explore its relevance in cognitive processes, adaptive stress response, neurochemical modulation, and inflammation-related signaling.

LYOPHILIZED PEPTIDES

This peptide is supplied as a sterile, freeze-dried (lyophilized) powder to maintain its molecular stability, purity, and structural integrity. No fillers, carriers, or excipients are added.

RESEARCH APPLICATIONS

1 — Anxiolytic & Stress-Response Modeling

Selank has been examined in laboratory settings for its impact on anxiety-related pathways, stress adaptation, and GABAergic modulation. Research highlights potential interactions with neuropeptide systems and regulatory networks involved in emotional processing.

(References: Nature—https://www.nature.com/articles/s41598-018-31261-9, PubMed—https://pubmed.ncbi.nlm.nih.gov/16465455/ )

2 — Neurotransmitter & BDNF Modulation

Studies suggest Selank may influence monoamine levels, enhance BDNF expression, and interact with GABA-related pathways. These mechanisms support its use in research exploring neuroplasticity, cognitive processing, and synaptic-regulation dynamics.

(References: ScienceDirect—https://www.sciencedirect.com/science/article/pii/S0166432816305516, PubMed—https://pubmed.ncbi.nlm.nih.gov/19639783/ )

3 — Immunomodulation & Cytokine-Regulation Studies

Selank has been evaluated for its ability to modulate cytokine expression, regulate inflammatory mediators, and influence immune–neuro communication. Research examines its effects on pathways linking immune activity to neurological processes.

(References: MDPI—https://www.mdpi.com/1422-0067/17/2/290, PubMed—https://pubmed.ncbi.nlm.nih.gov/19492432/ )

SPECIFICATIONS

Property | Details

Peptide Name | Selank

Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)

Chemical Name | L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline

CAS Number | 129954-34-3

Molecular Formula | C33H57N11O9

Molecular Weight | ~751.9 g/mol

Purity | ≥ 99% (HPLC verified)

Appearance | White lyophilized powder

Solubility | Soluble in bacteriostatic/sterile water

Storage | Store dry at −20 °C; refrigerate ≤ 30 days after reconstitution

Usage | Laboratory research only

Research Data & References

– BDNF & neurotransmitter modulation: https://pubmed.ncbi.nlm.nih.gov/19639783/

– Stress & neuroregulatory pathways: https://pubmed.ncbi.nlm.nih.gov/16465455/

– Immune signaling & cytokine pathways: https://pubmed.ncbi.nlm.nih.gov/19492432/

Disclaimer — Research Use Only

All information presented herein is intended solely for laboratory and educational research. These materials are not approved for human or veterinary use, nor for diagnostic or therapeutic application. Descriptions of biochemical activity are provided for informational context only and must not be interpreted as medical advice. Researchers are expected to handle all compounds in compliance with local regulations and institutional safety standards. EOC Labs supports responsible, ethical, and compliant scientific inquiry.